Exame de sangue que rastreia Alzheimer pode se tornar realidade

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[{"selector":"#anim-171987d3-f17a-4a97-8098-8993896534c4","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c94a1b37-d9d9-464c-8986-864aa1ba0723","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-186ae1dc-d73f-45ce-abbd-1c72c70a796e","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-929b82ae-0e61-4a98-8afd-641ca1c9c883","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Um novo tipo de exame de sangue, capaz de rastreiar a Doença de Alzheimer com “alta precisão” antes mesmo do início dos sintomas, pode se tornar realidade em breve, diz estudo publicado na segunda-feira (22) na revista JAMA Neurology Freepick

[{"selector":"#anim-ecf748a3-fabd-449d-a08f-f0cc4ef756a1","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-61b65dcd-1b19-4bba-a142-4a5f1b21e12d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-5d96ccbd-8c41-40a2-a5bc-efdc9e0973a4","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-630a4b85-c253-4913-a2fe-00a4061c893f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Isso seria possível a partir da identificação de um tipo de proteína no sangue, chamada tau fosforilada, ou p-tau Artem Podrez/Pexels

[{"selector":"#anim-3c62c044-b42c-4f36-8cbd-2c2965cde9e2","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1896803b-d715-4b98-8fe8-6d04130cf366","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-e203616a-f8c7-4f54-9b5a-cca4e6a7c88b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-dfa81ec1-52b7-4f86-bd61-c365c4154664","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Essa proteína funcionaria como um biomarcador, já que ela aumenta no sangue ao mesmo tempo que outras proteínas prejudiciais aumentam no cérebro de pessoas com a doença kjpargeter/Freepick

[{"selector":"#anim-ab4ba76c-e603-4b9d-b11b-9642aff41659","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b33ea147-c80f-4e7d-939f-130bc1a0c664","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-8d0faacf-d54b-4abd-af48-922f2724a474","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-1f64b720-398f-4fa4-a331-5a3897014721","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Atualmente, para identificar o acúmulo de p-tau no cérebro, os pacientes são submetidos a uma tomografia cerebral ou punção lombar, que muitas vezes pode ser inacessível e dispendiosa Anna Shvets/Pexels

[{"selector":"#anim-7370d900-557a-45ad-8a6e-84549cc58709","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-faba9dac-27c3-4da6-97cd-2d74cfbeba5e","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-386d9e24-6a6d-4f96-be47-6827619a4450","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-68b11e50-abaa-41b0-8e1a-852d35f67358","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e5af9fb6-605a-4154-9a35-9dc53be76aec","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-00f1b5c0-5cbc-4297-8a4b-896a1564444f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Mas descobriu-se que este simples exame de sangue tem até 96% de precisão na identificação de níveis elevados de beta amiloide e até 97% de precisão na identificação de p-tau, de acordo com o estudo Freepick

[{"selector":"#anim-2e4e714c-53f3-43bd-b688-80c6faae37d5","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-27a1fa5f-e1e0-410e-b9e5-6d592e1f554d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f178bbda-618f-44cd-a878-0d32b89672d3","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-e58b7ba9-b9dd-4d38-9d05-ab4f92bbe181","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] “Um biomarcador sanguíneo robusto e preciso permitiria uma avaliação mais abrangente do comprometimento cognitivo em ambientes onde os testes avançados são limitados”, escreveram os pesquisadores no estudo rawpixel.com/Freepick

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