Alzheimer: estudo mostra o que pode causar a morte de neurônios

[{"selector":"#anim-9bccab20-bb42-466a-91af-e2f71df29056","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ceb60c0e-b47f-4840-a70a-5b8e5db3c5b4","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2346eded-84e5-4b6b-a5b9-0a76c1f51e50","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-00c7a2c3-26fa-41f7-8f2f-99ce11aef378","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Pavel Danilyuk/Pexels

[{"selector":"#anim-c3b641fe-1981-48c0-9ad9-00880f3c3dd5","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ce4a5b61-7457-4173-9cb1-f528f283f51c","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-95cccc32-b9c4-43de-9f69-c09b724afe11","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-36e11f67-75e8-40e1-ad64-1f9295484a5c","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Pesquisadores da Northwestern University descobriram uma possível nova causa para a degeneração de neurônios na doença de Alzheimer vecstock/Freepik

[{"selector":"#anim-ff3f105b-aae7-479b-9e3a-8e6079d75899","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-14d78428-01cb-41de-8907-719275b7c4fb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-de1837c8-722d-44bb-8c5a-8f0e2e44c966","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-506541aa-df22-43a7-9351-68e540fa1def","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Segundo os autores, um mecanismo presente no RNA (ácido ribonucleico) pode estar envolvido na morte de diversas células, incluindo os neurônios kjpargeter/Freepik

[{"selector":"#anim-679cf1a6-763b-475e-aa0c-4c44512538e2","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-664f247f-b78f-4f2d-b20c-fc75605b9dcd","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d8f2de4e-361d-4fb1-8fac-e7f969265363","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d6e15e5f-e6e4-46b2-972a-9e22b752c805","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Foram analisados cérebros de três fontes: modelos de camundongos com doença de Alzheimer, neurônios derivados de células-tronco de pessoas com e sem a doença e adultos com mais de 80 anos Pixabay/Pexels

[{"selector":"#anim-35bac34b-c82a-4278-a10c-4ce47004ab4a","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e4660141-7d68-4c80-8d93-b3254a9275fd","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4fce06ec-3e18-4388-9c57-63ba6be5f071","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-a5a813df-b8c7-4bfd-b96f-d871c9cb98d0","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Os pesquisadores descobriram que uma espécie de “código” embutido em RNA curto com apenas seis nucleotídeos poderia matar células importantes kjpargeter/Freepik

[{"selector":"#anim-52f15d1a-1fd6-4167-8ac4-653d38809dc2","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ce34946e-8226-4d6b-9123-7e8f630a9204","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-558c6ae0-04e4-4e71-b3df-a3b17d38e7ce","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-a9c74eb7-0c7b-4950-92a9-eadf00225fbf","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] “Chamamos a sequência curta de ‘código da morte’. As células morrem porque os RNAs que carregam o código suprimem seletivamente os RNAm que codificam proteínas”, disse o cientista Marcus Peter kjpargeter/Freepik

[{"selector":"#anim-d6a3d695-1751-49c9-a4b0-a21eae59de89","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0c751813-e491-41b4-a564-b39177fb4617","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f2444cb8-b3d6-400f-aa05-8422a7233f0d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-ba617bd1-0251-40e1-b312-af29c7be8265","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Essa descoberta é importante para abrir caminho para novas pesquisas em torno do desenvolvimento de medicamentos para tratar o Alzheimer e outras doenças degenerativas Freepik

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[{"selector":"#anim-27d83f4b-4c17-42e4-a153-734ff645df11","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-18596c1a-a459-49bb-a38d-3eccc4e3ade8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b4f7aec6-e8e7-444e-979c-d57d09ce95d8","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-0d7eaf6d-3d97-410e-aa19-72f23be410ba","keyframes":{"transform":["translate3d(0px, 2132.63615%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d6201beb-7857-4dcc-be49-c7fe170b1a39","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-070a6057-33ef-409d-86e6-3d8f670b67c9","keyframes":{"transform":["translate3d(-117.84387%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2793019c-ba50-43f0-b586-0abc2c62b822","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-aeb3c1eb-5ba2-4c89-a50b-043c12d6dc4f","keyframes":{"transform":["translate3d(0px, 1223.93157%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] storyset/Freepik leia mais em