Antiviral para mpox não reduziu sintomas da variante mais perigosa

[{"selector":"#anim-ef5a6037-7c2f-4682-96d7-bf4c5ff57160","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-27a50279-40a6-48bf-9430-bcb5faee7285","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b03665ff-67ef-4202-8150-e631b7eb6e9f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-d3ff44ba-c06a-41e1-ac27-fb82177119ad","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] SERGII IAREMENKO/SCIENCE PHOTO LIBRARY/GettyImages

[{"selector":"#anim-9cb256a2-8ca1-4405-878e-02215ac38015","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-30dfb50d-6bb9-40f2-9d03-63f19b516451","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ea2b3a5f-cfeb-4b2f-b167-caaf791f6c7d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c531c3d6-9415-4008-9787-c7affde38903","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Uma análise inicial de um estudo clínico mostrou que o antiviral tecovirimat , utilizado para o tratamento da mpox , não reduziu a duração das lesões causadas pela doença em crianças e adultos infectados com o clado 1 Christina Victoria Craft/Unsplash

[{"selector":"#anim-1554d80b-ea56-49d6-bb9c-478da344c1fb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a943c4ee-4031-4848-94c6-776e12d8116d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b976454d-4cb0-484b-bff8-2fbaa6d4187d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-8f3ece8e-9376-484e-a97e-0a0ab54f04c1","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Essa variante é mais letal e é responsável pelo atual surto na República Democrática do Congo (RDC) Reuters

[{"selector":"#anim-a49b98e7-b6e4-4357-b9f0-d0a94557ab4f","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bf355d39-a11e-4125-a399-cbe132a0e920","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7a6e3d4f-d18d-4209-baa9-83dedf6e16d5","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-4e24ed97-6e3d-4e43-8766-8a99832dbc4a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Por outro lado, a análise observou uma mortalidade menor (1,7%) entre os participantes do estudo, independentemente de terem recebido ou não o medicamento, em comparação com a mortalidade por mpox entre todos os casos relatados na RDC (3,6%) Freepick

[{"selector":"#anim-04fafd47-35c3-450b-bbfd-11458cae7dea","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c70214a9-7198-4090-bcb0-7b2f95ee91f0","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2d4d740f-c276-40b7-881a-507466d33650","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-05b3e06f-d336-49ab-856f-1488f9216f26","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Isso significa que melhores desfechos de saúde podem ser alcançados quando pessoas com mpox são hospitalizadas e recebem cuidados de suporte de alta qualidade Freepick

[{"selector":"#anim-1a6f7b9c-cb2b-41da-8d5e-6ee88542e02d","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b69c8d59-5ecc-4d90-8f7a-225ef702f6aa","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-10792a0b-5a39-4483-980f-4bbbd2b9cd18","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f999d387-6058-4b29-9317-b5c8f70e68cb","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] O antiviral tecovirimat foi desenvolvido para o tratamento da varíola comum, mas foi licenciado em 2022 pela Agência Europeia de Medicamentos (EMA) para tratar mpox, com base em dados de estudos em animais e humanos Suzy Hazelwood/Pexels

[{"selector":"#anim-7ac395c4-3297-4c3c-85bd-27606e00ac89","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a68f3ded-353f-456d-9bde-563a00325df5","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-920e6f22-1362-43c0-a513-ab941b7463c7","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-3306be51-818b-4d66-882e-731654907409","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] De acordo com o Centro de Prevenção e Controle de Doenças (CDC) dos Estados Unidos, o tecovirimat pode ser considerado para tratamento em pessoas infectadas com o vírus da mpox com doença grave REUTERS/Arlette Bashizi

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