Estudo: Antibióticos podem aumentar risco de doença intestinal

Antibióticos podem aumentar risco de doença inflamatória intestinal, diz estudo

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[{"selector":"#anim-49cc7fdf-49b9-4bf2-90eb-e50960f79593","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-89252d7d-256c-470a-9181-bab772d66a76","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-41cba2ec-fdbc-49d1-bc92-a2933776c6f5","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-697edb43-4331-4f6a-8280-b8d076fe2f13","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-68ea46a2-cf3d-4a6e-a8be-c8e2c1818173 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.422334446094975%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Um estudo publicado na Science Advances sugere que o uso de antibióticos aumenta o risco de doenças inflamatórias intestinais (DIIs), como doença de Crohn e colite ulcerativa Unsplash

[{"selector":"#anim-1d23de7b-2831-4687-942e-1497e0272432","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3cc519c8-5ff5-4db6-a856-de68cafc5c83","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-134533d6-9037-4a14-8e4d-68884a1ab1b8","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-7b40b2de-aeea-4f4d-82ed-f39289d75188","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Os antibióticos podem danificar a camada protetora de muco do intestino, facilitando a infiltração de bactérias e aumentando a inflamação Unsplash

[{"selector":"#anim-5e51e919-ec60-4ada-bc7c-30b0fe7f70aa","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c3402041-bfb8-42a7-af1e-f228cda92844","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-7e2625dd-0366-4f6c-a943-28eadaff0b07","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-be5d0867-99b9-43ce-be8b-292fc455dcb9","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-84e59a4f-6c88-46e0-a065-916f8415506a [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] As DIIs afetam milhões de pessoas no mundo, e o estudo israelense lança nova luz sobre a relação entre o uso de antibióticos e o desenvolvimento dessas doenças Unsplash

[{"selector":"#anim-d4c74639-1d92-4eab-b884-5afefa1e7903","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-06a9ae0e-7935-480f-bca3-341d036dc9fb","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-bc22c53c-66ea-4e55-bc0e-b0da46a98c78","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-5b94b9bf-2b2e-4a02-bf5d-46170ababf89","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b64f7a7f-4eef-4983-99d4-2730d9cc018e [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(35.24305544178129%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Utilizando técnicas como sequenciamento de RNA, os pesquisadores descobriram que os antibióticos reduzem a secreção de muco, agravando a saúde intestinal Unsplash

[{"selector":"#anim-5c7284ae-e050-4260-81e1-38fc82d4b271","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ff7d2810-4f80-4963-8d06-c379ee395923","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-a8973ae8-0cc2-44c4-80d4-b4687c66d451","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-f76cb82f-2c82-41f9-b003-707006a6b329","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4b717e11-7bb8-4c1d-a014-deb70aeacca3 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(-13.888888939455242%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Além disso, foi observado que as células responsáveis pela produção de muco também são prejudicadas pelos antibióticos, desafiando a visão de que apenas bactérias são afetadas Unsplash

[{"selector":"#anim-b215d6e0-983a-4fa9-b7a0-8d5282ea2703","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-99d6e495-9179-4b88-8add-7b7ffaa3225d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-23b504bb-9e21-4eed-bdb6-c8a079db468a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-2aa5393b-2bcb-4f8a-82bc-5ecbee416e87","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-be608355-9d7f-40a6-bb38-6392f9a73cb6 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-20.83333321955906%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O próximo passo da pesquisa é desenvolver tratamentos que mitiguem esses efeitos adversos e reforçar o uso cuidadoso de antibióticos na prática médica Unsplash

CNNBRASIL.COM.BR

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