Antidepressivo pode ser eficaz para tratar tumor cerebral, diz estudo

Antidepressivo pode ser eficaz para tratar tumor cerebral, mostra estudo

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[{"selector":"#anim-d83a7fe2-287d-43dc-9243-cd2fc357e25c","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5ce7b737-ff0f-4db5-a807-7e9a47dd5234","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b7b0481e-78b2-4f91-aced-e7e51bb33870","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-3e699ae6-aff5-4200-9321-a4f3f2376d55","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-99410b8a-e65a-4c5a-9248-c2dbceebf320 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(7.762983898637003%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Pesquisadores descobriram que um antidepressivo chamado vortioxetina pode ser eficaz para combater o glioblastoma , um tipo de tumor cerebral agressivo e que, atualmente, é incurável cottonbro studio/Pexels

[{"selector":"#anim-a4b04485-bac1-4339-9a25-517c8c2d7511","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-30117741-36b3-4592-a9b7-9661b5a8af2c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-76d77e2f-15e0-4c2e-8e9d-340d40a53bd0","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d7bf2458-f7d1-401d-a68c-cc5b08a03f42","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-06df2750-0ca6-44a7-89a5-1ea6945e89d4 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(-3.552713678800501e-15%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Segundo cientistas, o medicamento é capaz de cruzar a barreira hematoencefálica para chegar ao cérebro e, potencialmente, eliminar o tumor, o que muitos remédios contra câncer não conseguem fazer Milad Fakurian/Unsplash

[{"selector":"#anim-23bf32dd-a981-44a2-a321-48ca6b7a330f","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d498b9b9-0dee-4844-8d05-21a7ce22511f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4b19c0a5-951d-4bfb-9c7e-68da243fa660","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-fbd2a0ab-4599-4519-895b-09a51c775d9b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-b309de31-8556-417d-84f6-b5645c6a8e1e [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.7629838986370086%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Segundo o estudo, alguns antidepressivos testados foram eficazes contra as células tumorais, principalmente quando desencadearam uma cascata de sinalização que suprime a divisão celular. Entre eles, a vortioxetina foi o antidepressivo mais eficaz no combate ao tumor Anna Shvets/Pexels

[{"selector":"#anim-9374300c-3bc6-44b7-b6c1-b126e1f403b0","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5ba28dcb-165c-45c8-b190-8cb8c074a79c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6dabe5f3-8c72-4eac-b96e-2d17e304f943","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-598bb4b0-fcec-4c6c-beb5-2635c6ee6ad7","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-70cd1987-fd3b-4eb9-914e-b0ed39f38e97 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.67480457630343%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Em seguida, eles testaram esse antidepressivo em camundongos com glioblastoma. Nesse teste, o medicamento também mostrou boa eficácia, especialmente em comparação com o tratamento padrão atual Pixabay

[{"selector":"#anim-e10dfff5-2e4e-4421-b6b6-eeb4bdf9054d","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a4e59086-d9df-4c76-b600-fb4bbf5a472f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1ea3a999-354c-41fa-aac7-176c24b6afc0","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-41ce3137-32bd-48d4-ae8e-64ad55d2781c","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-c7a26d38-4c42-41da-ac21-ea4d51eccb22 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(7.105427357601002e-15%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] “Como o medicamento já foi aprovado, ele não precisa passar por um procedimento de aprovação complexo e pode em breve complementar a terapia padrão para esse tumor cerebral mortal”, diz Michael Weller, professor do Hospital Universitário de Zurique Karolina Kaboompics/Pexels

[{"selector":"#anim-b533940f-8bda-4a01-860a-2e81065a05bc","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7e00a4f3-43db-479a-b033-0d96ff6f2908","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d1332b05-22c7-4b0b-a8fd-cd67016ad2ee","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2cc31005-e2da-4546-9910-a7205edeb0cb","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-765e771f-8481-4575-b190-7485f3dc3828 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.833582952531623%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] “Ainda não sabemos se o medicamento funciona em humanos e qual dose é necessária para combater o tumor, razão pela qual os ensaios clínicos são necessários. A automedicação seria um risco incalculável”, orienta Freepick

CNNBRASIL.COM.BR

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