CAR-T: como é tratamento contra o câncer anunciado pelo governo

CAR-T: como é tratamento promissor contra o câncer anunciado pelo governo

[{"selector":"#anim-20ef2680-dd1c-4cce-a20f-a5c109d93373","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-13a81031-3902-4b91-a6f7-cf22478d4a4f","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-7efc404d-5372-4eb0-9dc6-015424496e28","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-39f8610a-dc95-41f0-8a61-ce0132c4a8e8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Solskin/GettyImages

[{"selector":"#anim-fd287ef4-9df8-49bd-944b-b4807aeda272","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a09dd98b-6b9c-4709-9db2-a4c81f86df35","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d798ca37-4b52-4433-b289-909c9cf665eb","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2cd2cd76-ff63-43d5-b193-14ee4d2a1bd2","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-9ec28479-08cf-476b-8ae6-33e9b6b55b80 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(53.73931613721113%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O ministro da Saúde, Alexandre Padilha, disse que o Brasil pretende desenvolver a terapia CAR-T contra o câncer em território nacional, através de uma parceria com os países do Brics Reprodução/TV Brasil

[{"selector":"#anim-167ddb8b-5ee2-4ac5-9cf0-eb8a7e726b83","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2d8f59e4-77d4-45a5-b500-525ba9eee0ac","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1b9582f4-b505-4d60-97c3-a304969a7c59","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-15e3a6c5-d738-4da5-8aeb-274c7fc115fc","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] O novo tratamento contra o câncer utiliza as células do sistema imunológico do próprio paciente, que são geneticamente modificadas para atacar as células cancerígenas Artem Podrez/Pexels

[{"selector":"#anim-73e1c1c8-91a8-4adb-b88d-ce803e7dbd7a","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d169cd2b-8ffd-4d59-8525-8ea268d0721d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-336b36e3-59fe-4728-b452-b4c59f09615e","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2e955121-1c05-4352-8a6c-09a8a4a7652b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] "São drogas vivas, chamadas de terapia celular, que aprimoram o sistema de defesa do paciente para que ele promova a cura através da destruição das células do câncer", explicou Renato Cunha, hematologista e líder nacional de terapia celular da Oncoclínicas Anna Shvets/Pexels

[{"selector":"#anim-fd7a9fc6-3b92-4de9-8bb7-961bcf30027b","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b92c9ec0-c8a5-46f6-99fd-2bcda762b6d4","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2492a5c3-74ce-43ea-8eeb-0f4dc2d31ca3","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c5abec9a-116d-411e-b180-7aa64d5d0132","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-98976143-186e-4ad3-9676-d948d3b4efa8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.249999886225726%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Em um processo similar à hemodiálise, chamado aférese, as células T são extraídas do sangue do indivíduo e enviadas para laboratórios especializados, onde serão modificadas geneticamente Pixabay

[{"selector":"#anim-012ccff1-50c5-4cc1-a718-e72c1153f487","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ddbb70a8-8bca-4ed5-9d16-52d3b13e971a","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f6322ac4-c129-488e-ad18-a1a548b26467","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-335b9307-6d46-4f53-b7fd-67646da80584","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Essas células são recolocadas na corrente sanguínea do paciente, com a função de se multiplicar e atacar as células que formam tumores cottonbro studio/Pexels

[{"selector":"#anim-530d754c-000b-45cb-815c-cb9c842e96cf","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-72e2cb2c-38c9-474d-9c64-e9ea6d5d3c1e","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-41997793-a06e-4433-970b-3abc9093e1bf","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b687619f-cfd7-4c4a-911e-2cf673cacf0b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-5d7cf3af-3b23-47a1-a461-33e755487843 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.248436083046933%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Atualmente, o tratamento pode ser realizado apenas para tratar um número limitado de cânceres que afetam o sangue – como leucemias, linfomas e mieloma múltiplo. Os resultados têm sido promissores nesses casos Tima Miroshnichenko/Pexels

[{"selector":"#anim-cbe88313-6ff0-49ba-9bed-938c48fd5a0f","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bf663588-d44c-4a8f-8e34-acc6e5f858a3","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-85e7250b-ab2c-4470-8bec-aac2ffedcab8","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-9ffcc854-ab61-4a30-889f-69b44d6e645b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] O principal desafio da terapia CAR-T, no entanto, é o seu custo elevado: o processo todo pode custar entre R$ 2 milhões e R$ 3 milhões por paciente. A nacionalização do tratamento anunciada por Padilha pode ser uma maneira de reduzir o custo Freepick

CNNBRASIL.COM.BR

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