"Ozempic oral" não retarda progressão do Alzheimer, aponta estudo

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[{"selector":"#anim-ecc0a5cb-979e-4195-98e7-dc58b23d78dd","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b395b0cf-f2d3-49d0-b855-e63d9905da35","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b953f5af-1c78-49a9-a27b-16676be8c1ef","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-658e4a09-a50e-49d0-a560-c007664cca82","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e37a19b3-d671-4b9f-b2ac-2fded5f5c3d7 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] A Novo Nordisk anunciou que a versão oral da semaglutida (princípio ativo do Ozempic e Wegovy) não conseguiu retardar a progressão do Alzheimer em testes clínicos de Fase 3 Unsplash

[{"selector":"#anim-a4e102f5-df03-49ec-958c-8502c3043168","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4e056d36-8206-4c5d-b861-b002fc2eab1c","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d2408ed2-c5a6-40c5-a9ee-9eb67d1e52d2","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-2001d975-b0fb-4faa-9707-1620c6eb3ddd","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-dc86f832-40cb-4cb2-a854-984baf657836 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.249999886225726%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os ensaios envolveram mais de 3.800 adultos que estavam recebendo tratamento padrão para a doença Unsplash

[{"selector":"#anim-f2c34e19-37d0-421b-983e-248671055f47","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e13b9ea1-2ac0-4039-b52e-b1b7a596b581","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f69535b3-012d-48fc-a2ab-ce535eb51bd9","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-52ac5a63-f57f-413a-a3d3-b2435baed107","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-87d35a6a-bbcc-46f3-8975-d5a429d575b8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-31.249999886225726%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A empresa reportou que o medicamento demonstrou ser seguro e levou a melhorias em biomarcadores relacionados ao Alzheimer Unsplash

[{"selector":"#anim-036f4430-6119-4326-915e-7b3d99f50aac","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d43a2804-4e11-4edb-9cb8-d167d26e67e1","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-66d18af1-f6c4-4a5f-bba0-238fb257439d","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-66559637-e319-43e1-be8d-56f0e049a2d9","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9535d10d-92d7-4699-8d98-9a4be0b0a4db [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(53.66956498892992%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Contudo, a medicação falhou em seu objetivo principal, que era desacelerar o declínio cognitivo e a progressão da doença Unsplash

[{"selector":"#anim-47422c55-6d42-48c4-b5f3-dca280a0cb79","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-aaa64c54-2f00-4728-a660-78409bd8f38a","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2a910d25-dec0-40c4-bad1-aba1d34b7b6a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-fc8dffc4-5d92-4657-a0af-b20cbee932d7","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] A Novo Nordisk afirmou que sentiu a responsabilidade de explorar a semaglutida devido à grande necessidade não atendida na doença de Alzheimer Unsplash

[{"selector":"#anim-39e30fad-6b81-4899-9c09-089f23de1beb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7eb7d232-3088-4dca-b861-b50e90ef51f6","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d5eb6f52-c000-4f2e-a3a4-67ea3c1becb4","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-da3f3321-f84c-4cbd-b7dc-f00856fedf27","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-77c1188c-07f9-4bc5-ba1e-91a668288c60 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0, 18.032786885245912%, 0)","translate3d(0, 0%, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Como consequência, a extensão de um ano dos ensaios será descontinuada, e as ações da empresa caíram após o anúncio Unsplash

CNNBRASIL.COM.BR

[{"selector":"#anim-fdeaf605-c1b1-4f85-b8cd-018593dcbd41","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e13171e8-68d8-43a9-92b5-f0d92cd4b3aa","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b32cbd26-8b27-4282-82f3-7eb8e79cf169","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a87a1cdf-8b8f-4fe4-90bb-bcfaaa42b93b","keyframes":{"transform":["translate3d(0px, 2132.63615%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4ef3019c-72a2-4ffe-a1a6-06cb2c2c4c31","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-73a4da96-90bf-49b7-ba7b-6cc5c5238f03","keyframes":{"transform":["translate3d(-117.84387%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-dd15eba7-12c2-4751-afbf-b29a5ab1edd7","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-facbde42-cc74-4969-ba9c-ecd7b73374eb","keyframes":{"transform":["translate3d(0px, 1223.93157%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Unsplash leia mais em