Cientistas editaram gene que pode reduzir colesterol alto

Cientistas editaram gene que pode reduzir colesterol alto permanentemente

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[{"selector":"#anim-a4515f6f-8cbe-4e86-933c-2e07738930fb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7b568a08-922b-4a66-a3af-6a7ea49d44e4","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d418e57d-9c21-42ec-8aa4-ee207b23b8ca","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-1258212f-8fd5-4f80-8a66-6a0af22141fd","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7cc0ba59-e504-4a0b-a325-349b263ad179 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(15.489130795797083%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Médicos testaram um tratamento que usa edição genética para reduzir permanentemente o colesterol alto , com resultados iniciais promissores Unsplash

[{"selector":"#anim-e0924219-e7fc-44f2-816f-09cdeffa35d2","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bdbd8aa5-5fb7-4ca9-bde3-885dd1975c82","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-6c6465e1-8b53-4a6c-b01e-c44aa9252de4","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-39d9f761-7cdf-417d-a5b9-9a2fad4a7545","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-32ac4a8c-cd86-42eb-99a9-d3f87338ad5b [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-24.891304054183884%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O estudo piloto, com 15 pacientes, usou CRISPR para desativar o gene ANGPTL3 e conseguiu reduzir o LDL em quase 50% e os triglicerídeos em cerca de 55% Unsplash

[{"selector":"#anim-a12150ea-65ce-437e-93b0-27d045679faa","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3eb386ee-7756-45ce-a6c4-659f9a411525","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-212dc2f8-8c00-4a2c-b87b-2cb41f3b2824","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-6d22919d-06c6-4ad3-8d95-3c71cbd9974e","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-86a47be8-3c0e-4e51-83dd-1a86ee0eb551 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0, 10.714285714285708%, 0)","translate3d(0, 0%, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A proposta é oferecer uma terapia única, capaz de substituir medicações diárias e manter o colesterol baixo ao longo da vida Unsplash

[{"selector":"#anim-8a832026-f697-4551-a7a3-e6c2ee99f808","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-193004d2-034e-47a0-83f9-dc218d234c3a","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-5d078665-8509-4ba1-a9b2-56bb13120041","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-e384dff5-f0b1-4212-aafd-f0ba8de91c86","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] A inspiração veio de pessoas que já nascem com esse gene inativo e naturalmente têm níveis reduzidos de gordura no sangue sem prejuízos à saúde Unsplash

[{"selector":"#anim-e4af7a53-5f80-44fc-8b4d-983315b6153b","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c7c534a9-af64-4f7e-930f-fe789da959e8","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-a04ba772-cca0-4a1d-9609-5ea20fe178ef","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-74f4378f-191b-473f-9bd9-d33c4a9c637b","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9f5887a3-52b6-463c-8815-648b984e0d51 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(15.489130795797083%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os efeitos colaterais foram leves, mas os pacientes serão acompanhados por 15 anos para avaliar a segurança a longo prazo Unsplash

[{"selector":"#anim-dd0596d9-322e-4439-9971-6598692d3da9","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-25aabf90-8271-4145-bde2-1210b1ac3b08","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-4564afb6-dbcf-4739-8349-38ad58a8732d","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-071c4058-a7de-4462-a531-f0adb6ca909e","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e790ed27-ee93-4c4b-a346-5659d7d40e49 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.8167392676995755%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Agora, o tratamento seguirá para as fases 2 e 3 de testes, mas especialistas reforçam que quem usa remédios para colesterol deve continuar o tratamento atual Unsplash

CNNBRASIL.COM.BR

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