Cientistas identificam 3 compostos naturais que impedem replicação do coronavírus

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[{"selector":"#anim-8bd42506-d4e2-428c-a094-d1e170402133","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8c1e01c9-8676-41a6-a06f-782e50266ebc","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a28b52f8-11d7-41b1-9ed6-459a55892e97","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8e2dd3a1-d97d-4b1d-9205-21d44630643d","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-838af309-79ed-42f3-b9c2-89eb996be8dd [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(19.173366706291645%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Edward Jenner/Pexels Cientistas brasileiros e estrangeiros identificaram três compostos para o tratamento da Covid-19

[{"selector":"#anim-e254cfd4-176d-4088-8f84-9706119c2c3f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(21.467391131213066%, 0, 0) translate(25%, 0%) scale(1.5)","translate3d(0%, 0, 0) translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.14,.34,.47,.9)","fill":"forwards"}] [{"selector":"#anim-10f65bac-0b53-4a79-8dae-e87beec390e1","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cc25aab3-265e-4da3-a96e-b7a10a46733b","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-05afb31b-2813-40ef-9951-64a0502d47df","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d6322e52-ef34-4bae-94cc-2e1ababd31f6","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] CDC/Pexels São compostos naturais selecionados em uma triagem com 500 fármacos, que se mostraram promissores em inibir a proteína PLpro – uma das enzimas responsáveis pela proliferação do SARS-CoV-2

[{"selector":"#anim-6f007157-41b7-4701-b847-45e7ff45902e","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6c7230d0-80f7-446f-b8fd-48c0f2e9525b","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-01fa34ae-f76e-4954-813b-4a6ac8a85177","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a300e022-d144-4dd6-9318-47bb38689324","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7385e862-2402-4da3-ac38-9a2f5484f88c [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(28.499680990322958%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Todos os três compostos são derivados do fenol e classificados como polifenóis, uma classe de compostos bioativos presentes em plantas Chokniti Khongchum/Pexels

[{"selector":"#anim-e6a7c640-696b-4151-bbdc-30ec5d8c2f6a","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fbd14e40-b2be-4ae3-9c85-ca75adac17cd","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cda8c76c-9048-413d-a0d5-6a71fc77f38d","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a3155977-d792-4ebc-ba88-5e670d753d03","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6197e15e-ee91-4633-b887-8cdffc176881 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-15.581929043650284%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os testes foram feitos em células Vero (linhagem oriunda de rim de macaco) e comparados com um grupo de células que não recebeu os compostos Ludwig Kwan/Pexels

[{"selector":"#anim-280270cf-1e55-4e60-b4bc-b8723d43824d","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b0f50c75-327e-4d4c-a314-fa5d75b7b44e","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ca0c3c91-9073-4edf-ae30-929d58152c3b","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a2cf84da-46dd-4221-9e79-965ddff46c02","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f514a14b-8116-4f48-ad80-5f48c0a0d5a2 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(15.581929043650284%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A linhagem Vero possui similaridades com a célula humana e é muito usada como modelo experimental nesse tipo de estudo Polina Tankilevitch/Pexels

[{"selector":"#anim-82b8321a-f846-4ee1-8c35-47307bf6c4c8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-15.581929043650284%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-152c1973-47de-4ef4-915a-b41ecd5a289b","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ce6378ba-7cf5-4461-be51-e03eb7dc2afb","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5f5b47ad-14cb-4196-a9c8-56ab923230be","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1e18a355-85a8-4a9a-932c-906b7b06c434","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] ThisIsEngineering/Pexels “Como um percentual considerável dos vírus não conseguiu se replicar, as partículas virais infecciosas foram eliminadas”, explica Edmarcia Elisa de Souza, pós-doutoranda da USP

[{"selector":"#anim-50486b15-9a8a-4f1b-9fdb-80529b3026ba","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a920842a-8c4f-4895-b1ce-a06f3de32174","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8b0f4312-571b-43ba-9473-ebe6bee31a95","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3ad5bdec-4d83-4f7c-9741-71fbb216a27c","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2258f8b6-750f-40c9-a918-04b10c448717 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(19.47277788220481%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O próximo passo é fazer testes em modelos animais para avaliar melhor a eficácia dos três compostos. Caso seja bem-sucedido, será possível avançar para os testes clínicos Chokniti Khongchum/Pexels

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Cientistas identificam 3 compostos naturais que freiam o coronavírus

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