Cientistas revelam processo de infecção celular pelo coronavírus

IMAGENS DE MICROSCOPIA

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[{"selector":"#anim-59ea0b37-cabf-4039-b45e-d14b629bae2d","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e86e6447-6622-4126-96d8-453ac44ad94b","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6bddf986-2c0d-430b-8967-4135504ffa24","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6eb8c5aa-9cf2-45b4-93b0-064346bfca8e","keyframes":{"transform":["translate3d(-118.35205%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8a94bd91-a57a-436d-a356-a9e57ca4fcc8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(19.997667334007136%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Foram utilizadas células Vero, amplamente estudadas na compreensão dos mecanismos de infecção viral e no desenvolvimento de potenciais tratamentos contra doenças Barreto-Vieira et al; Viruses

[{"selector":"#anim-76d71b3d-8e36-4f76-a69c-0e3273bd1a1a","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7860e7f4-2d67-4070-9172-4dfac5a90496","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ff281c69-7274-4612-881e-5ec8102e88e2","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5f4cf84e-1f82-4c88-85ea-846c1ef91de4","keyframes":{"transform":["translate3d(-118.35205%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6b1601ce-4f37-4444-807a-fc9be8ca00d3 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(10.15455571632837%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A pesquisa revela como o vírus invade a célula, além de identificar onde ocorrem importantes etapas da replicação viral e o momento de liberação das novas partículas virais Barreto-Vieira et al; Viruses

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[{"selector":"#anim-5f505bfe-5006-44b9-9ef2-74adede5c4f7","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c3d78a23-7412-4d92-adeb-d3e01f60ebc8","keyframes":{"transform":["translate3d(-85.14851%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8db0a044-53d9-4016-82ac-b7a39b364bda","keyframes":{"opacity":[0,1]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b9fe7f45-1f9f-4363-add1-14b73b0f182f","keyframes":{"transform":["translate3d(-117.97753%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":800,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-575198bf-9bdb-453a-8c11-4fe02d261e36 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(24.876847966450008%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] As imagens foram obtidas por meio de microscópios de última geração disponíveis no Instituto Nacional de Metrologia, Qualidade e Tecnologia (Inmetro) e na Universidade Federal do Rio de Janeiro (UFRJ) Divulgação/Cenabio/UFRJ

“Precisamos de modelos in vitro bem caracterizados para desenvolver fármacos que atuem em diferentes etapas do ciclo viral. Nesse estudo, conseguimos descrever o ciclo replicativo do SARS-CoV-2”

[{"selector":"#anim-28491021-11d6-4bc9-ac3a-4b470f5afe47","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f510d980-4519-4039-b7d2-6a61ae5f58b9","keyframes":{"transform":["translate3d(0px, -190.96618%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-36dbfe72-dc68-40c3-ae51-a9bbb1ac1460","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ee7db46e-bd9a-407c-953d-16910c6833d6","keyframes":{"transform":["translate3d(-126.49254%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Débora Ferreira Barreto Vieira, cientista da Fiocruz

IMAGENS DE MICROSCOPIA

Cientistas revelam processo de infecção celular pelo coronavírus

“Precisamos de modelos in vitro bem caracterizados para desenvolver fármacos que atuem em diferentes etapas do ciclo viral. Nesse estudo, conseguimos descrever o ciclo replicativo do SARS-CoV-2”

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