Como a obesidade do pai afeta o metabolismo dos filhos?

Como a obesidade do pai afeta o metabolismo dos filhos? Cientistas explicam

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[{"selector":"#anim-9166b192-102e-474f-8cf4-5804d1c54015","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5cca637a-5725-4d00-9b41-7a47ce88c273","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f3e45d92-9cc1-46de-a184-8d1fa0d092b6","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-c4d2de2f-ccb3-4de2-9049-69b1db7045f5","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a6f866d6-bfaa-4426-88a1-f1a69e18360c [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-40.87354169247642%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Um estudo publicado na revista Nature Communications identificou que essa “herança” ocorre por meio de alterações no espermatozoide Unsplash

[{"selector":"#anim-a520229a-828a-4d30-b7fc-9f714a31d564","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7fa07938-867f-4349-8b86-9eff868c9323","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-46493bd5-d595-4103-b540-b2c8965053bb","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-6dc896ef-2752-463f-9ac1-3cf33f988468","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4343b496-d49e-4225-a1c9-d710ff9499bc [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(21.87766532141289%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Em testes com camundongos, a prole de machos obesos desenvolveu intolerância à glicose e resistência à insulina ao longo do tempo, caracterizando uma disfunção metabólica silenciosa Unsplash

[{"selector":"#anim-0a30a5c8-7fb7-4cbf-a48b-b3bf3556c1a6","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8e35124f-d274-4529-b7d2-a12683592e2b","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-7337e403-a4d3-4186-b735-34069bf8ae0e","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-5253edb1-c254-48fc-adb0-f7c63c17f0a4","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-30155c2c-7ba1-49be-9cc8-6e1d6daa0b3e [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.812499744007886%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os cientistas descobriram que microRNAs do tipo let-7, elevados no sêmen de indivíduos obesos, afetam o embrião ao inibir a enzima DICER, prejudicando o funcionamento das mitocôndrias Unsplash

[{"selector":"#anim-f25f464c-232e-4023-9a0e-c5f0431ab2c6","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1049ec87-40e3-4e5e-9f7b-4ddf79b0a831","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-4fc03a70-9709-4404-aff9-06028c11c165","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-cd23e546-2817-4a5d-af06-0edb744c3c61","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c212dc93-a5df-42b7-97d6-c978424e00a2 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(9.646738861981813%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Isso altera de forma duradoura como o organismo dos descendentes lida com energia, aumentando o risco de diabetes tipo 2, com impacto mais forte nos machos Unsplash

[{"selector":"#anim-1f0e33f7-083a-44ca-bbde-374cde7c3571","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-159bf17e-da43-4fe8-aef3-01adf024c8c5","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d787efab-38a0-489c-b17f-3822bb72172a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-d0223523-a8bf-4c1b-84f3-b1317cf516d4","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Por outro lado, a perda de peso dos pais reduz esses marcadores no sêmen e pode reverter o efeito, fazendo com que os filhos nasçam metabolicamente saudáveis Unsplash

CNNBRASIL.COM.BR

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