Como o antirretroviral oral molnupiravir pode mudar o tratamento contra Covid-19

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[{"selector":"#anim-782323f9-4fd7-4179-87f6-3d417745b0bf","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-300d08f7-fe1a-45a8-a03f-a66afe25025f","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-355b28bd-9824-42ea-9214-897a710e3a80","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-48d1ff78-89ca-42df-9575-a5c1e5ae4692","keyframes":{"transform":["translate3d(-116.27119%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-84e15890-3cf4-4fd5-a325-98211529587f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(30.962800759756536%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A pílula antirretroviral contra Covid-19 molnupiravir, produzida pelos laboratórios Merck Sharp & Dohme, pode significar o primeiro tratamento contra Covid-19 por comprimidos Reprodução / Merck Sharp & Dohme Corp

[{"selector":"#anim-88e37baa-c7c0-423a-afbc-eb00e7227ad3","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1ca25f34-decd-4eb0-94f9-366d16bec140","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b38fd53a-dd97-44b6-a5db-622adfeabb2d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a4a3cbaa-26a2-4420-9c65-28b366b67fc6","keyframes":{"transform":["translate3d(-115.93221%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-77f44c54-fe3f-4f1f-8bd1-4f5ac6a1b8cb [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-51.8011472895404%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O uso da pílula diminui pela metade a chance de alguém com Covid-19 ser internado ou morrer pela doença, segundo estudo mais recente com o medicamento. O Reino Unido aprovou seu uso no país no início deste mês Reprodução / Merck Sharp & Dohme Corp

[{"selector":"#anim-e834a052-a12e-4c6b-bd03-e2b91d5912fb","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8767f887-ba46-4f2d-900d-878645341f9d","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-97aadd1e-8d3c-438d-9280-d339332756cd","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cff05daa-d8f0-48d3-833f-ef5fbd9dc6c5","keyframes":{"transform":["translate3d(-115.93221%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7bb4df69-bcd9-49ba-bee0-dd231b566d3f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(34.179687404002955%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os dados ainda não foram revisados ​​por pares ou publicados, mas geraram entusiasmo sobre um tratamento potencialmente fácil e acessível para Covid-19 Viktor Forgacs / Unsplash

[{"selector":"#anim-72b401de-0061-4968-81d2-b5ab53ad3799","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-636b612d-8887-4a11-9783-a6fc5b136ed2","keyframes":{"transform":["translate3d(-135.12397%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cccae650-be39-4aec-a312-5b9c6db2be9d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a8b65daa-6c4a-4686-a2b8-bd5f686afa15","keyframes":{"transform":["translate3d(0px, -238.88889%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-dad06d41-a3ad-48b7-876a-b6e14ff109d3","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d48659c4-eac5-40cb-a833-1149d03a3fd3","keyframes":{"transform":["translate3d(0px, 198.18586%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Tratamentos antivirais que podem ser tomados em casa para manter as pessoas com Covid-19 fora do hospital são extremamente necessários Wendy Holman, diretora executiva da farmacêutica Ridgeback Biotherapeutics, que está colaborando com o trabalho

[{"selector":"#anim-ba136593-4b22-4f44-955e-2abe034cc7c9","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-caec1149-bdc8-4004-94c2-8aa53ce0c5b4","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d523e13f-efd7-4bcd-9d35-8d5a8f9b35b0","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-598d3a43-843e-4254-947d-02dc364051cf","keyframes":{"transform":["translate3d(-116.26298%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6283237f-d309-46f0-98e4-ff44511b696d [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 2.733316014845931e-7%) scale(0.9009009009009009)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Porém, a pílula não chega como uma substituta das vacinas, que estimulam uma resposta imunológica, mas como um complemento para combater a pandemia, interrompendo a replicação do vírus Reprodução / Merck Sharp & Dohme Corp

[{"selector":"#anim-06473884-ca51-4142-81ca-47f76ca5a663","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7c4e70e8-4aff-48cf-8454-546d2174a13f","keyframes":{"transform":["translate3d(-135.12397%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5cce6478-518d-4d60-8fde-4c03d46bd5ea","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4527b11a-700a-4823-989e-95f394ee5634","keyframes":{"transform":["translate3d(0px, -238.88889%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9b864e05-9464-43a9-949d-7658b6c7a19b","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b7826faf-ccf3-47d5-9ce9-be2d4162e8fb","keyframes":{"transform":["translate3d(0px, 269.75295%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Como terapêutica oral, o molnupiravir oferece um acréscimo importante às vacinas e medicamentos implantados até agora para combater a pandemia de Covid-19 Dean Y. Li, vice-presidente executivo e presidente da Merck Research Laboratories

[{"selector":"#anim-709d03a0-115e-4c83-9f10-d7a7aebf6999","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4b8612ff-6ba9-4700-ae63-52386dee52f0","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cf9f6e8b-40ed-4982-8e29-6cb29a2aa086","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4815b8da-1f5c-4efa-adab-e7256c95c9fa","keyframes":{"transform":["translate3d(-116.21622%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-8cb7f303-0907-472e-96fa-1caf3e3b92c3 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(26.4640547844869%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A pesquisa com o molnupiravir foi realizada com 775 pessoas em mais de 170 países, incluindo o Brasil, onde foi feita em São Paulo, Brasília, Belo Horizonte, Curitiba, São José do Rio Preto (SP) e Bento Gonçalves (RS) Reprodução / Merck Sharp & Dohme Corp

[{"selector":"#anim-f0c5f6ab-dd64-489a-a648-6dd95e75ff2d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2f92aff2-49ba-47cf-bea5-c8d77a4dbe8c","keyframes":{"transform":["translate3d(-100%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-419d26df-2918-4818-bae3-fa1ca84442b8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1680cf14-4427-4d04-8a71-311f4f8e312e","keyframes":{"transform":["translate3d(-116.21622%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-83796742-0e78-49f0-9a3d-a4515c7190f6 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0, 5.357142857142854%, 0)","translate3d(0, 0%, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Ainda no Brasil, a Fundação Oswaldo Cruz (Fiocruz) está trabalhando em dois estudos globais de fase 3 do molnupiravir, visando avaliar os resultados preliminares de eficácia e da tecnologia necessária para a produção do medicamento no Brasil Reprodução / Merck Sharp & Dohme Corp

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