Corpo pode produzir próprio “Ozempic” após modificação genética

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[{"selector":"#anim-06949c40-d2b5-40bd-945f-61031900a3cf","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7763e2b4-33f9-4ead-90aa-d43d4b4f9d24","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4d9a681b-bb5e-4188-b3bb-2c3190af7464","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-91d390a7-e948-4823-89a7-4ed85d48810f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Um estudo inovador confirmou que um tratamento genético único , ou seja, uma injeção intravenosa de nanopartículas lipídicas, foi capaz de fazer o corpo produzir seu próprio remédio contra obesidade e pré-diabetes Artem Podrez/Pexels

[{"selector":"#anim-c6fe248a-510f-4450-9f1b-d09bfd82000d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e1115285-23a1-4cb0-b7b7-ea5c6d5fc2ba","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-59026d6c-9acf-451a-ad81-cf4ff17a71a9","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b5a7c5e0-37ac-4155-bee2-423a2a01956d","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Freepik Além da alta eficiência terapêutica, os efeitos foram duradouros e seguros

[{"selector":"#anim-ce1a55e0-ae5a-4f78-8698-bee0fdc7ac77","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-88d0f36c-6431-4af9-a1d7-4f59a91b6b34","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1c2a2e2d-9e84-4383-90be-1388f0814ffc","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c65cbaf7-3b73-46e6-9db6-cd579666740d","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] ThisIsEngineering/Pexels Cientistas da Universidade de Osaka, no Japão, relatam uma “edição genômica in vivo para introduzir um gene que codifica o agonista do receptor do peptídeo semelhante ao glucagon-1 (GLP-1), Exendina-4, modificado com um peptídeo sinal de secreção”

[{"selector":"#anim-bd28f110-bfb3-4e57-bc1c-5e892e7586ed","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-52c7fc0d-7971-465d-b821-ddd4f4db01ab","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ed6b4d34-7d47-44a4-8141-0921c160f417","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-70771c16-061a-4cd5-abc7-be0e2b58d1e6","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Na prática, significa que os pesquisadores modificaram geneticamente ratos de laboratório para que seus fígados se transformassem em uma espécie de “fábrica interna” de exenatida Ricky Kharawala/Unsplash

[{"selector":"#anim-e56562e7-5a89-4be2-966e-e14f4de7a436","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-04f09fe0-374f-4af4-805e-c5a7aa2f9f52","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-97f45121-0352-4717-95d9-b7a98358332f","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-f416b7d9-d7ce-49e7-8343-6c6a4f920318","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Exenatida é um medicamento antidiabético que pertence à classe dos agonistas do receptor de GLP-1, o mesmo que é ativado pelo Ozempic Carsten Snejbjerg/Bloomberg/Getty Images

[{"selector":"#anim-7d73ccc9-5136-428e-85a5-30ac8c90b038","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-71ac26f6-2c87-4218-bbac-3a399a380c78","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-cfc85b73-7530-41ed-b589-68addfb4457e","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-8e9b16c4-3fa5-4a0a-aeea-05a0ce55986e","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Só que, diferentemente do famoso medicamento, os ratos mantiveram o remédio no organismo por meses sem precisar de injeções, e apresentaram melhores resultados de saúde Sandy Millar/Unsplash

[{"selector":"#anim-a0d196f6-5604-44a3-a14c-72f1d9e0016d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-36ace0f0-9f89-4eca-a532-87185e37d28e","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-73b6af86-3cbc-438f-aec7-6814964dc7f6","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b5f11f47-e442-4c92-ab1c-8f553980b72d","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Freepik Aplicações futuras em humanos poderiam teoricamente permitir uma produção permanente de medicamentos GLP-1

CNNBRASIL.COM.BR

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