Covid-19: o que ainda falta entender sobre a infecção?

[{"selector":"#anim-bbd0c4e0-0335-4375-88b3-3bbc353d40eb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b300c637-f110-4902-80f2-2db12d37f062","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-cba113d2-b104-4339-ac85-7b0eecd571a1","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-ac2100b8-46ba-4f59-9fa8-03807a1de0bd","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Unsplash

[{"selector":"#anim-bf1c80c1-da23-4d3f-803d-f6d3e1f37f95","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ed2b856a-4a8e-48d8-b703-a279181953b2","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-e6f39311-3efe-482f-b465-9a3426409082","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-9ced9620-a14d-45dd-8c0b-18f4934aaf7c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-15fef524-f03b-442a-b83a-b4891c5a2295 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(34.179687404002955%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A pandemia da Covid-19 começou há cerca de cinco anos em Wuhan, na China, com um vírus altamente mutagênico que ainda desafia a ciência devido à sua capacidade de escapar do sistema imunológico Unsplash

[{"selector":"#anim-3cd4ad00-e3fc-4a2b-b85b-19133b530b10","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b15de646-e0cd-4b78-ba99-a5f20b5a5ca2","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d306768c-9280-4a84-83f3-524494a2ff1a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-ca2814e1-bf32-41a0-a2a6-44aa407d8923","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f6d3f48d-4f90-4fe6-a9fb-384ce6683179 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-35.24305544178129%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Um dos grandes mistérios em estudo é a Covid longa, caracterizada por sintomas persistentes mesmo após a infecção, sem consenso sobre por que alguns pacientes desenvolvem essa condição Unsplash

[{"selector":"#anim-967301e2-cd12-490b-827c-7e7ce03e2546","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b6d240ac-fa7f-4ed1-b2c8-afc599a7dabf","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-8f460cef-3ad2-4c15-954f-d966337f0666","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-872676de-22da-4cd2-ad80-f31f44c55231","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Estudos indicam que fatores como falta de vacinação completa, obesidade e tabagismo aumentam o risco de Covid longa e agravam sintomas como dores de cabeça e perda de olfato Unsplash

[{"selector":"#anim-920084ab-1df5-4be0-bda2-628e9de8be32","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ec548a26-79a0-4ea3-9d1c-de62980c5705","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c9ba5515-2d0a-4edd-beac-0423a6bf24d7","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-986f5f94-a610-44a8-a143-90e1092e1342","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1f1eea71-6617-44d9-b4bb-1d37945682e3 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(21.87499990400296%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Também não está claro por que algumas pessoas são mais suscetíveis a reinfecções, embora fatores genéticos e imunológicos estejam sendo investigados como possíveis explicações Unsplash

[{"selector":"#anim-7ca80911-8da8-4717-9036-473c1d647636","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bb77c35f-b78b-4b5b-9dcb-b55301f504c4","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-60ebb8c9-e264-4d59-876f-02ee712631f0","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-08c86a93-afe0-4542-a23f-4609773f896b","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Pesquisas sugerem que indivíduos resistentes ao vírus podem ter características genéticas, como alterações na proteína Spike ou expressão elevada de certos genes relacionados à resposta imune Unsplash

[{"selector":"#anim-97f9e04c-3a85-41da-b80b-16c9aa8052c8","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1bcf94cb-0c29-4c92-90e8-09ef4dd7e286","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-31f8263a-9501-45d9-a6e3-84abd3fc8691","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-18f45670-f6a1-481b-86f2-2bbe610c01c9","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c46fa80e-9c29-4831-9f4b-ed036f36df8b [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(31.249999886225726%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Estudos avançados com tecnologias de sequenciamento e análises genéticas em pares sorodiscordantes ajudam a desvendar essas diferenças, mas ainda há muito a descobrir sobre o comportamento do vírus e as respostas humanas Unsplash

CNNBRASIL.COM.BR

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