Diretriz muda tratamento do diabetes tipo 2 e reacende debate

Diretriz britânica muda tratamento do diabetes tipo 2 e reacende debate

[{"selector":"#anim-0c89a563-f1ac-4003-924a-bf85bfeb243f","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-49b36887-5d55-4361-b52a-cee07fddc40f","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d3ee8edd-822b-4e8b-9fb0-1757c54172b0","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-5b125c29-29ae-4cc4-b0fe-d8496c41715b","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] i-SENS, USA/Pexels

[{"selector":"#anim-95e52cb9-0bf6-4074-b9c4-d5a3bc312ef4","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-35d60a35-06d3-4365-b267-8bdbfe26db65","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-5b9e92f9-7bff-4857-b350-56f822b6326a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-f68d5607-7e35-455c-a16a-399d934f945f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a5dd1bb6-7650-41f6-8c9f-2ea25b53ac33 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(7.264147590646562%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] O tratamento do diabetes tipo 2 está em transformação. A atualização da diretriz NG28 do National Institute for Health and Care Excellence (NICE), órgão responsável por orientar políticas clínicas no Reino Unido, reposiciona o foco terapêutico Nataliya Vaitkevich/Pexels

[{"selector":"#anim-4cb8f5fb-34df-429e-b8cf-d9504bb964c9","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4d66ee87-fcc8-468b-88ad-3e7547601d8e","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-d88a793a-18d8-4de7-8f44-f060868c04ee","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-9e6dce55-a575-43d0-8462-0dab8a5eaec8","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fea42e23-f658-4748-b41e-eed2998bb30e [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-32.51450898041378%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Controlar a glicose continua essencial, mas proteger coração e rins desde o início do tratamento torna-se prioridade explícita nesta atualização Pexels

[{"selector":"#anim-38ad8b9e-9a1e-4489-ba00-66d2a62a9923","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-f00ccd34-fb81-448a-a7c2-a3e2106992ba","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-08a182ce-a6c0-457e-9a8a-5415dd5fb812","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-fdad831f-58fc-453e-b456-b37d7c8441f7","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-93268e66-a168-4f60-8814-c731b8dcf6f5 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0, -10.20550218974248%, 0)","translate3d(0, 0%, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Essa mudança, no entanto, não ocorre isoladamente. Ela dialoga e em alguns pontos diverge das recomendações da American Diabetes Association (ADA), principal referência nos Estados Unidos Pavel Danilyuk/Pexels

[{"selector":"#anim-149d1207-1946-4423-a800-76be58e8d513","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-911774a4-7efc-474a-9594-75359a7ec8ef","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-8ab20ede-099e-4d2a-a6fe-4855d52f4b61","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-2ec24dc8-5b8a-46bc-85f6-d8cfe8485fc1","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9304d802-58d1-4c9c-afcf-908dc0fadddf [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-47.96584561996629%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Hoje sabemos que grande parte das mortes em pessoas com diabetes decorre de doença cardiovascular e insuficiência cardíaca e não apenas da hiperglicemia isolada. A nova diretriz do NICE incorpora essa evidência ao recomendar uso mais precoce de medicamentos com comprovado benefício cardiovascular e renal Pexels

[{"selector":"#anim-1872a134-f635-4138-9fd9-30552a4f5d62 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(0, -12.916779363655534%, 0)","translate3d(0, 0%, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-61ff6b9a-41e8-4776-9269-6c5fd363a010","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1352e9ca-641d-448f-8c29-4b2c2941cc6d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-dbeb74a4-fea9-4ed5-8535-e4c9ba5e6481","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-277f66db-14b5-436f-9f2d-cf92df2b498a","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] A ADA mantém a metformina como terapia inicial tradicional na maioria dos casos, salvo contraindicações ou presença de alto risco cardiovascular, onde SGLT2 ou GLP-1 podem ser iniciados precocemente Nataliya Vaitkevich/Pexels

[{"selector":"#anim-7f2cac1b-86c8-408e-a55e-052973d771c6 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(-0.6706550728353571%, -4.353940129697167%) scale(0.8695652173913043)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-19267b3d-9e5a-4734-8140-0048c5b26ac6","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-dad093b6-4e27-4149-a261-e1a31d7fe185","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-0720053c-acfb-4429-b5d5-a8140663a353","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-b2489f8b-61a1-4afd-90eb-c61c589fba3f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] A ADA enfatiza fortemente obesidade como alvo terapêutico prioritário, inclusive defendendo metas agressivas de perda ponderal e uso de terapias específicas para redução de peso Pixabay/Pexels

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