Estudo: nova pílula para diabetes é mais eficaz do que "Ozempic oral" 

Nova pílula para diabetes é mais eficaz do que "Ozempic oral", diz estudo

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[{"selector":"#anim-d93784b9-4314-46c9-9ae7-31677f9d472b","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7ca1a9db-34cb-45b9-8ca2-bed9a98a4434","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c9bcfa28-b9af-4bb9-923b-3c4b2171e608","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-392c93e1-7caa-465d-825f-09515d4f67ba","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-7c5e4a89-f325-4121-b425-9f086504fc3e [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(48.91709905328229%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] A Eli Lilly anunciou que sua nova pílula para diabetes, à base de orfogliprona, apresentou resultados superiores à semaglutida oral na redução da hemoglobina glicada e na perda de peso Unsplash

[{"selector":"#anim-8cc29730-8b14-4418-b021-0487c78532ba","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b58d3171-b841-4382-81ae-c45a9a43310e","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-807062ab-14ee-4e93-b63d-a81082ff59ec","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-7cf7492e-bc3f-404f-a4b0-f686a4ed3b24","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d2cd73bf-cc79-4434-90d0-ac1a60f6f03a [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] O medicamento pertence à mesma classe dos agonistas do receptor GLP-1, como Ozempic, Wegovy e Mounjaro, mas tem como diferencial a administração oral Unsplash

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[{"selector":"#anim-f5350741-0a93-4ee7-8294-561d75a44f9b","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-3abefa93-1890-41e3-b5c6-237fa9f464e4","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-159629a2-406f-4788-abf6-b59a5899b0e5","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-8fdc4257-de68-497b-86f5-67f0b9d59079","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Os pacientes também perderam em média 8,9 kg com a dose mais alta do novo fármaco, em comparação a 5 kg obtidos pelo concorrente Unsplash

[{"selector":"#anim-eae75155-0ce3-4f95-9a27-d16ddc1e4e75","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-03e0d23f-68b2-4dc8-9533-e7b0e4eae953","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-86ee2197-7f44-4a79-a202-bd57c9a54683","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-6e3d0fbf-62e5-4787-8794-81b0dda48ff6","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-ec49bab5-0d3b-4519-8ec5-a629c1a59294 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(49.86413019455364%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os testes duraram 52 semanas, com 1.698 adultos com diabetes tipo 2 não controlado por metformina, e mostraram perfil de segurança consistente, embora com mais efeitos gastrointestinais e maiores taxas de descontinuação Unsplash

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CNNBRASIL.COM.BR

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